Baco Blanc or Baco 22A is a French-American hybrid grape variety. In the 20th century it was widely planted in the Gascony region for uses in brandy production. Both Armagnac and Cognac (from the Charentes and Charente-Maritime districts north of Gascony) are brandies made from white grapes - Ugni Blanc, Folle Blanche and Colombard - but only Armagnac was permitted under French regulations to use Baco Blanc and until the late 1970s, Baco Blanc was the primary grape of Armagnac.

Following the grape's decline in the late 20th century, there was some speculation about the future of the variety, especially after a 1992 Institut National des Appellations d'Origine (INAO) decree that all vines of Baco Blanc were to be uprooted by 2010. However, advocates for the grape variety and its historical role in Armagnac were able to persuade French authorities to continue permitting its use in the distilled wines from the Armagnac region